• 11380 Prosperity Farms Road, Suite 204–208 Palm Beach Gardens, FL 33410
833-STEM561
833-783-6561
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833-STEM561
833-783-6561
MUSE-Infused RPA™ Therapy

Advanced Acellular Regenerative Protein Therapy for Joint Health & Recovery

Experience the latest innovation in regenerative medicine with MUSE-Infused RPA™ Therapy at RegenOrtho Palm Beach. This advanced acellular therapy combines Regenerative Protein Array™ (RPA) technology with proteins extracted from MUSE cells to support your body’s natural healing response through targeted biological signaling.
Designed for patients seeking advanced non-surgical orthopedic care, MUSE-Infused RPA Therapy offers a personalized treatment approach to help support tissue repair, reduce inflammation, and improve mobility.
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Overview

Next-Generation Regenerative Medicine Without Living Cells

MUSE-Infused RPA Therapy represents one of the newest advancements in regenerative medicine available at RegenOrtho Palm Beach. Unlike live-cell therapies, this treatment is acellular and non-DNA, utilizing a specialized protein array enhanced with proteins naturally extracted from MUSE cells.
These biologically active proteins are designed to support communication between cells, helping coordinate the body’s natural repair processes while promoting a healthy healing environment.
Every treatment begins with a comprehensive physician evaluation, imaging review, and personalized treatment plan to determine whether MUSE-Infused RPA Therapy is appropriate for your condition.
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How It Works

A Personalized Five-Step Treatment Process

1

Comprehensive Consultation

Your physician performs a complete orthopedic evaluation, reviews your medical history, symptoms, imaging, and treatment goals.
2

Imaging & Diagnosis

MRI, ultrasound, X-rays, or other diagnostic imaging help determine the most appropriate regenerative medicine approach.
3

Customized Treatment Plan

Based on your diagnosis and lifestyle, your physician develops a customized treatment strategy using advanced orthobiologic therapies.
4

MUSE-Infused RPA™ Therapy

Your physician delivers MUSE-Infused RPA™ Therapy through IV push or targeted injection to help support tissue repair and recovery.
5

Recovery & Follow-Up

Most patients return to light activities quickly. Regular follow-up appointments allow your physician to monitor progress and optimize your recovery plan.
Common Conditions We Treat

MUSE-Infused RPA Therapy May Be Considered For

Our physicians commonly evaluate patients experiencing:

Knee Osteoarthritis

Hip Osteoarthritis

Shoulder Arthritis

Ankle & Foot Arthritis

Chronic Tendon Injuries

Ligament Injuries

Plantar Fasciitis

Persistent Joint Pain

Sports Injuries

Inflammation Management

Treatment Method

What Is MUSE-Infused RPA™ Therapy?

MUSE-Infused RPA Therapy combines Regenerative Protein Array™ (RPA) technology with the protein fraction extracted from MUSE cells. According to the brochure, it is an acellular, non-DNA therapy that delivers regenerative proteins rather than living cells. These proteins help support direct biological signaling involved in tissue repair, anti-inflammatory activity, angiogenesis, and cytoprotective processes.

Treatment Includes

  • Comprehensive orthopedic evaluation
  • Diagnostic imaging review
  • Personalized regenerative treatment planning
  • Physician-directed IV push or targeted injection
  • Recovery recommendations
  • Scheduled follow-up appointments
Treatment Method

Initial Consultation & Imaging Review

$300

Consultation fee is credited toward treatment.

Treatment Starting From

$2,500

Pricing varies based on the treatment plan and physician recommendations discussed during your consultation.

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Meet Your Specialists

Experienced Physicians in Regenerative Medicine

Dr. Orlando Cedeno, DPM

Dr. Cedeno received his bachelor’s degree in chemistry from the University of Pittsburgh. In 2006, he graduated from Barry University School of Podiatric Medicine & Surgery in Miami, Florida. Subsequently, he completed a three-year surgical residency in reconstructive and trauma surgery of the foot and ankle at the Chestnut Hill Hospital/University of Pennsylvania in Philadelphia.
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Dr. Marc Matarazzo, MD

Dr. Marc F. Matarazzo is a board-certified and fellowship-trained orthopedic surgeon with over 20 years of experience specializing in sports medicine and minimally invasive arthroscopic surgery. A Fellow of the American Academy of Orthopedic Surgeons and an active member of the American Orthopedic Society for Sports Medicine, Dr. Matarazzo is dedicated to providing advanced orthopedic care.
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Patient Guide & Answers

MUSE-Infused RPA Therapy is an acellular regenerative medicine treatment that combines Regenerative Protein Array™ technology with proteins extracted from MUSE cells to support the body’s natural healing response through protein signaling rather than living cells.
Traditional MUSE Cell Therapy uses living MUSE cells, while MUSE-Infused RPA Therapy uses an acellular protein fraction enhanced with proteins from MUSE cells. According to the brochure, RPA delivers signaling components rather than living cells.
Depending on your physician’s recommendation, treatment may be provided through IV push or targeted injection as part of your personalized treatment plan.
Your physician will determine whether MUSE-Infused RPA Therapy is appropriate after reviewing your symptoms, medical history, physical examination, and diagnostic imaging.
Most regenerative medicine procedures are completed in under one hour, although treatment times vary depending on your individualized care plan.
Regenerative medicine therapies are generally self-pay services and are not covered by insurance or Medicare.

Important Medical Information

Newly available at RegenOrtho Palm Beach. None of the therapies described are FDA-approved to treat, cure or prevent any disease or condition, and they are not a substitute for indicated surgical care. Composition and mechanism characteristics are drawn from published literature and supplier documentation, not from RegenOrtho Palm Beach outcomes. Cellular products are HCT/Ps from accredited U.S. suppliers; per 21 C.F.R. § 1271.3(d) cell factors such as RPA are not classified as HCT/Ps. Donors are U.S.-based, screened and tested by third-party CLIA laboratories. Individual results vary and no outcome is guaranteed. This material is general education, not medical advice. Services are self-pay and are not covered by insurance or Medicare.

RegenOrtho Palm Beach delivers concierge orthopedic, podiatric, regenerative, and vein care with trusted expertise, innovative treatments, and compassionate support.

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